Sean O'Conner
Lecturer
General Chemistry
Phone: (864) 656-1537
Office: 267 Hunter Laboratories
E-mail: oconns@clemson.edu
Dr. O’Connor received his B.S. degree in chemistry with special attainments from Washington and Lee University, Lexington Virginia. His M.S. degree in organic chemistry was from the University of South Carolina. He obtained his Ph.D. from Clemson University, also in the field of organic chemistry. His dissertation work involved ring-opening reactions of 5- and 6-member nitrogen heterocycles. He has taught organic chemistry at the University of South Carolina as well as general chemistry and organic spectroscopy at the University of Miami, Florida. He worked in the pharmaceutical, biotech, and aerospace industries as a research organic chemist for almost thirty years and joined the Clemson Chemistry Department in August 2005.
Publications
“Six-membered ring systems: pyridine and benzo derivatives.” Comins, D. L.; Dinsmore, J.; O’Connor, S. Prog. Heterocycl. Chem. 2004, 16, 303.
"Product Subclass 21: α-Lithioamines" R. E. Gawley, S. O'Connor, and R. Klein, Science of Synthesis (Houben-Weyl), vol. 8, V. Snieckus, ed. Thieme: Stuttgart, 2005, pp 735-814.
“Six-membered ring systems: pyridine and benzo derivatives.” Comins, D. L.; O’Connor, S. Prog. Heterocycl. Chem. 1997, 9, 222.
“New ring systems from 1,2-benzothiazole 1,1-dioxides and related compounds.” Abramovitch, R. A.; Shinkai, I.; Mavunkel, B. J.; More, K. M.,; O’Connor, S.; Ooi, G. H.; Pennington, W. T.; Srinivasan, P. C.; Stowers, J. R. Tetrahedron 1996, 52, 3339.
“Asymmetric synthesis of 2-alkyl(aryl)-2,3-dihydro-4-pyridones by addition of Grignard reagents to chiral 1-acyl-4-methoxypyridinium salts.” Comins, D. L.; Goehring, R. R.; Joseph, S. P.; O’Connor, S. J. Org. Chem. 1990, 55, 2574.
“Regioselective substitution in aromatic 6-membered nitrogen heterocycles.” Comins, D. L.; O’Connor, S. Adv. Heterocycl. Chem. 1988, 44, 199.
“?-Metalation of 1-(tert-butoxycarbonyl)-1,2-dihydropyridines.” Comins, D. L.; Weglarz, M. A.; O’Connor, S. Tetrahedron Lett. 1988, 29, 1751.
“The addition of alkylzinc iodides to 1-(phenoxycarbonyl)pyridinium salts.” Comins, D. L.; O’Connor, S. Tetrahedron Lett. 1987, 28, 1843.
“Tricyclo[6.3.0.01,6]undecan-2-one and its isomerization to tricyclo[3.3.3.0]undecan-2-one.” Cargill, R. L.; Dalton, J. R.; O’Connor S.; Michels, D. G. Tetrahedron Lett. 1978, 19, 4465.
“Antimotility and antisecretory activity of some aryl substituted amidinoureas.” Douglas, G. H.; Diamond, J.; Studt, W. L.; Mir, G. N.; Alioto, R. L.; Auyang, K.; Burns, B. J.; Cias, J.; Darkes, P. R.; Dodson, S. A.; O’Connor, S.; Santora, N. J.; Tsuei, C. T.; Zalipsky; J. J.; Zimmerman, H. K. Arzneimk.-Forsch. 1978, 28, 1433.
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